목록CUT&Tag (2)

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[ Cut & Tag / Cut & Run ] Cut & Tag 투토리얼

해당 글을 https://yezhengstat.github.io/CUTTag_tutorial/#Cite_this_tutorial 을 참고하였습니다. CUT & TAG Data Processing and Analysis Tutorial 1. Introduction Eukaryotic nucleus DNA에서 일어나는 모든 dynamic process 는 chromatin landscape/지형 을 따른다고 보면된다. Chromatin landscape 는 nucleosomes, their modification, TF and chromatin-associated complexed 등으로 이루어져있다. 이렇게 다는 chromatin features 을 이용하면 다른 cell type간, development..
Bioinformatics/Tools 2023. 3. 18. 05:05
[ Bioinformatics 논문 ] "An efficient targeted nuclease strategy for high-resolution mapping of DNA binding sites"

"An efficient targeted nuclease strategy for high-resolution mapping of DNA binding sites" Skene and Henikoff Jan, 2017 Abstract Cleavage Under Targets and Release Using Nuclease (CUT & RUN) Cut & Run 역할: quantitative high-resolution chromatin mapping probing(자세히 조사) of the local chromatin environment 장점: Simple, robust, need ~1/10th the sequencing depth as ChIP (low background data) 따라서 in situ..
논문 2022. 9. 27. 06:55
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